NIPT Service for healthcare professionals

IONA® Care – Extended menu

IONA® Care is a non-invasive prenatal screening test for pregnant women offering an extended test menu.

In addition to screening for Down’s, Edwards’ and Patau’s syndrome (trisomy 21, 18 and 13), IONA® Care screens for sex chromosomal aneuploidies (SCA) and autosomal aneuploidies (AA), offering a menu-based approach where pregnant women and their healthcare providers can select whether they would like to screen for SCA, AA or both.

The extended screening menu offered by IONA® Care (SCA and AA) is only available for singleton and monochorionic twin pregnancies.

Health Trisomies by NIPT
Core Menu
Extended Menu
Comprehensive Menu
Iona test
Iona Care
Iona Care Plus
Trisomy 21 (Down’s syndrome)
Trisomy 18 (Edwards’ syndrome)
Trisomy 13 (Patau’s syndrome)
Fetal sex determination*
XO (Turner syndrome)*
XXX (Trisomy X)*
XXY (Klinefelter syndrome)*
XYY (Jacobs syndrome)*
All other autosomal aneuploidies*
DiGeorge syndrome*
Other clinically relevant microdeletions*

* for singleton and monochorionic twin pregnancies only

Extended Menu - Including SCA and AAs'

Turner syndrome

(45, X)
seen in about 1 in 2,000 live female births

Trisomy X

(47, XXX)
seen in about 1 in 900-1,000 live female births

Klinefelter syndrome

(47, XXY)
seen in about 1 in 500-1,000 live male births

Jacobs syndrome

(47, XYY)
seen in about 1 in 1,000 live male births

Test Highlights

Sample type
IONA® Care turnaround time
High Accuracy
High Accuracy

Features

  • Suitable for women from 10 weeks gestation
  • Suitable for single and monochorionic twin pregnancies
  • Suitable for IVF or surrogate pregnancies
  • Optional fetal sex determination (not suitable for dichorionic twin pregnancies)
  • Unsuitable for women who have cancer, received an organ transplant, carry a chromosomal imbalance, had a transfusion of heterologous cells in the last year or who have complete or partial monosomy X (Turner Syndrome)
Yourgene Health

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If you have a question, need further information, or are interested in offering our NIPT service to your patients, we're here to help.