The IONA® test has been validated on a highly flexible and scalable workflow, suitable for low to high volume sample throughput, enabling clinical laboratories to meet and grow with their rising demands. It is available as both an automated and manual workflow.
The IONA® test directly measures the change in the proportion of chromosome 21, 18 and 13 in maternal plasma samples using a whole genome, shotgun sequencing approach. This is achieved in just 3 days using the highly automated and validated IONA® test workflow to give the highest quality results with the lowest amount of hands-on time (HOT) possible. All steps from DNA extraction through to analysis are included, eliminating the need for lengthy validation and optimisation processes.
Yourgene offer a range of library preparation kits for the manual and automated workflows, depending on the sample throughput, to meet the needs of your laboratory. The IONA® test has been validated on sequencing platforms from Thermo Fisher Scientific: Ion Proton™, Ion S5™/Ion GeneStudio™ S5, Ion S5™ XL/Ion GeneStudio™ S5 Plus/Ion GeneStudio™ S5 Prime.