Prenatal screening has been revolutionised over the last ten years with the emergence of non-invasive prenatal testing (NIPT) enabling vast improvements in accuracy and precision through the detection of circulating fetal DNA (cfDNA) in maternal blood. Non-invasive prenatal testing has been so successful since its introduction that it has since been called the vanguard of genomic medicine. NIPT is a screening test, and all high-risk results must be followed up with a confirmatory invasive test.
Why NIPT is important?
Our NIPT tests reduce the risk of false positives occurring, giving clinicians the confidence to refer mothers for an invasive test only when there is a high risk that the fetus is affected. This means fewer pregnant women will undergo unnecessary invasive follow-up procedures such as an amniocentesis or chorionic villus sampling (CVS) which can be stressful, painful and may carry a small risk of miscarriage.
The IONA® test – the first CE-IVD NIPT kitted product
NIPT was first launched as a super-lab service offering in the USA and China, but the market need for clinical laboratories wishing to run their own local NIPT service created great clinical demand. In 2015 Yourgene (formerly Premaitha Health) launched the IONA® test (CE-IVD) and changed the NIPT screening landscape. The IONA® test was the pioneer, the first to market as an IVD kitted product, enabling the democratisation of NIPT for a network of clinical laboratories globally.
Yourgenes NIPT Solutions
Today, Yourgene has a comprehensive offering of non-invasive prenatal screening tests, utilising next generation sequencing workflows, that have been built with labs in mind, and clinical prenatal screening services in the UK and Taiwan.
IONA® Nx NIPT Workflow
CE-IVD Illumina NextSeq 550 Dx Sequencer
the IONA® test
CE-IVD Thermo Ion Torrent Sequencer
Sage™ Prenatal Screen
RUO Thermo Ion Torrent Sequencer
Yourgene Nx NIPT Workflow
LDT Customisable Workflow Illumina NextSeq 500 Dx Sequencer